IGF-1 LR3 is a research peptide analog of human insulin-like growth factor 1 (IGF-1) containing a 13–amino acid N-terminal extension that enhances stability and receptor binding. It interacts with the IGF-1 receptor to activate PI3K/Akt and MAPK/ERK pathways involved in cellular growth, differentiation, and metabolic regulation. IGF-1 LR3 is used in experimental models to study peptide-mediated anabolic signaling, receptor kinetics, and tissue remodeling mechanisms.
For research use only. Not for human consumption.
References:
Yakar S et al., Endocr Rev, 2001 22(6):803–817
Bach LA et al., Mol Cell Endocrinol, 2018 473:1–9
Humbel RE et al., Eur J Biochem, 1990 190(3):445–462
